Hiroshi Hashizume Selected Research

Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)

3/2002

Epidural injection of cyclooxygenase-2 inhibitor attenuates pain-related behavior following application of nucleus pulposus to the nerve root in the rat.

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Hiroshi Hashizume Research Topics

Disease

12	Pain (Aches) 09/2022 - 08/2000
10	Spinal Stenosis (Stenosis, Spinal) 04/2024 - 09/2013
5	Spondylolisthesis 04/2024 - 01/2002
4	Pathologic Constriction (Stenosis) 12/2023 - 07/2012
4	Lordosis 10/2023 - 10/2017
4	Congenital Abnormalities (Deformity) 11/2022 - 05/2017
4	Low Back Pain (Lumbago) 11/2021 - 02/2007
4	Hyperalgesia 02/2007 - 08/2000
3	Osteoarthritis 11/2023 - 03/2018
3	Scoliosis 10/2023 - 09/2013
3	Spinal Cord Diseases 12/2021 - 12/2015
3	Neoplasms (Cancer) 01/2021 - 06/2013
3	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 01/2019
3	Sciatica (Sciatic Neuralgia) 01/2020 - 08/2000
2	Diffuse Idiopathic Skeletal Hyperostosis 11/2023 - 09/2023
2	Kyphosis 01/2023 - 01/2022
2	Osteoporosis 08/2022 - 03/2018
2	Radiculopathy (Radiculopathy, Cervical) 04/2012 - 08/2000
2	Intervertebral Disc Displacement (Herniated Disc) 02/2007 - 08/2000
2	Asthma (Bronchial Asthma) 06/2003 - 06/2003
2	Conjunctivitis 06/2003 - 06/2003
1	Osteophyte 12/2023
1	Spondylosis 11/2023
1	Knee Osteoarthritis 11/2023
1	Joint Diseases (Joint Disease) 11/2022
1	Frailty 08/2022
1	Sarcopenia 08/2022
1	Hemorrhage 01/2021
1	Hematoma 01/2021
1	Femoracetabular Impingement 01/2021
1	Pseudarthrosis (Pseudoarthrosis) 08/2020
1	Compression Fractures (Compression Fracture) 10/2018
1	Rheumatoid Arthritis 03/2018
1	Back Pain (Backache) 01/2018
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 04/2015
1	Mood Disorders (Mood Disorder) 11/2013
1	Spinal Diseases (Disease, Spinal) 09/2013
1	Spinal Cord Compression 05/2009
1	Hypesthesia (Numbness) 02/2007
1	Ganglion Cysts (Ganglion) 02/2007
1	Allergic Rhinitis 06/2003

Drug/Important Bio-Agent (IBA)

3	Prostaglandins DIBA 01/2021 - 06/2003
2	Ringer's LactateIBA 01/2021 - 01/2019
2	Plasma GasesIBA 01/2019 - 01/2019
1	pentosidineIBA 11/2023
1	TitaniumIBA 09/2023
1	polyetheretherketoneIBA 09/2023
1	Insulin-Like Growth Factor I (IGF-1)IBA 08/2022
1	Insulin-Like PeptidesIBA 08/2022
1	Thrombin FDA Link 01/2021
1	GelatinIBA 01/2021
1	SolutionsIBA 01/2021
1	Sodium Lactate FDA LinkGeneric 01/2021
1	Indicators and Reagents (Reagents)IBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	AntioxidantsIBA 01/2019
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019
1	AutoantibodiesIBA 03/2018
1	Dopamine D4 Receptors (Dopamine D4 Receptor)IBA 04/2015
1	Silk FDA Link 04/2012
1	AcidsIBA 02/2007
1	sarpogrelateIBA 02/2007
1	Hydroxyindoleacetic AcidIBA 02/2007
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 02/2007
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 02/2007
1	Serotonin (5 Hydroxytryptamine)IBA 02/2007
1	5-HT2A Serotonin Receptor (5 HT2A Receptor)IBA 02/2007
1	Bone Morphogenetic Protein 7IBA 09/2005
1	salicylhydroxamic acid (SHAM)IBA 09/2005
1	Anti-Allergic Agents (Antiallergic Agents)IBA 06/2003
1	ProstaglandinsIBA 06/2003
1	bicyclo(2.2.1)hepteneIBA 06/2003
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 03/2002
1	4- (5- (4- chlorophenyl)- 3- (trifluoromethyl)- 1H- pyrazol- 1- yl)benzenesulfonamideIBA 03/2002
1	CytokinesIBA 08/2000
1	Methotrexate (Mexate)FDA LinkGeneric 08/2000
1	fluoresceinated methotrexate (FMTX)IBA 08/2000
1	Immunosuppressive Agents (Immunosuppressants)IBA 08/2000
1	Immunologic Factors (Immunomodulators)IBA 08/2000

Therapy/Procedure

15	Decompression 12/2023 - 01/2002
9	Spinal Fusion (Spondylosyndesis) 10/2023 - 01/2002
8	Laminectomy 04/2024 - 12/2013
4	Laminoplasty 12/2021 - 05/2009
3	Therapeutics 01/2019 - 06/2013
2	Pedicle Screws 01/2022 - 01/2021
2	Endoscopes 11/2021 - 12/2013
2	Conservative Treatment 10/2018 - 10/2014
1	Foraminotomy 12/2023
1	Osteotomy 10/2023
1	Activities of Daily Living (ADL) 11/2022
1	Physical Therapy Modalities (Physical Therapy Technique) 09/2022
1	Operative Surgical Procedures 09/2022
1	Pain Management 09/2022
1	Kyphoplasty 10/2018
1	Minimally Invasive Surgical Procedures 07/2012
1	Aftercare (After-Treatment) 02/2007
1	Epidural Injections 03/2002